Research Associate (Crossley Group) (Fixed Term)
Role Overview
The Crossley Lab is recruiting a postdoctoral researcher to investigate how RNA-DNA hybrids contribute to human disease and could inform cancer diagnosis and treatment.
The research programme is supported by long-term funding from Cancer Research UK and the Wellcome Trust.
Key Skills for This Role
Full Job Posting
Role overview
The Crossley Lab is recruiting a postdoctoral researcher to investigate how RNA-DNA hybrids contribute to human disease and could inform cancer diagnosis and treatment.
The research programme is supported by long-term funding from Cancer Research UK and the Wellcome Trust.
Research opportunities
- Study pathological R-loops and their effects on genome stability in cancer and neurodegeneration.
- Investigate cytoplasmic RNA-DNA hybrids in innate immune signalling.
- Study extracellular RNA-DNA hybrid release and communication between cells.
- Use genomics and computational approaches to study RNA-DNA hybrids in cellular and patient-derived samples.
Research approaches
- The group offers opportunities to develop and apply long-read sequencing, proteomics, quantitative imaging, and functional genomics.
About you
- A PhD in a relevant discipline, awarded or submitted before appointment.
- A strong interest in cancer biology, genome biology, RNA biology, immunology, computational biology, or a related field.
- Excellent scientific, communication, and collaborative skills.
- Researchers with experimental, computational, or combined backgrounds are welcome.
Research environment
- Support is available for publications, fellowship applications, and career development.
- Researchers have access to specialist facilities, high-performance computing, and training.
- The group works in a collaborative research environment on the Cambridge Biomedical Campus.
Fixed-term funding
- Funding for the post is available for two years in the first instance.
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