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Scientist

Genomics
GBR
Full-time
Mid-Senior
Hybrid
Discovered 1 months ago
StatisticsRegression and statistical modellingGeneticsMolecular biologyStatistical programmingPython

Full Job Posting

Location and working arrangement

  • The role is based in Oxford or London with hybrid working.

About Genomics

Genomics combines large-scale genetic and health data with proprietary analytics to support drug discovery and predictive, preventative healthcare.

Its work includes AI-enabled genetic analytics and polygenic risk scores for improving prevention, screening, and treatment decisions.

Role overview

The Scientist is an early-career member of the Life Sciences team.

The role covers therapeutic target discovery, target validation, and patient stratification strategies.

The successful candidate will analyse large and diverse omic datasets using statistical or AI and machine learning approaches.

Example responsibilities

  • Generate therapeutic hypotheses and analyse disease biology using in-house data and statistical approaches.
  • Identify and triage potential targets with genetic evidence and assess relevant cells, tissues, patient populations, and biomarkers.
  • Apply and optimise risk tools combining polygenic risk scores with conventional risk factors for patient stratification.
  • Develop and execute rigorous scientific approaches and communicate findings to internal and external stakeholders.

Required foundations

  • Statistics, including modelling and regression.
  • Genetics and molecular biology.
  • Statistical programming using Python or R.

Preferred experience

  • Statistical genetics methods such as GWAS, colocalization, fine-mapping, Mendelian randomization, and polygenic risk scores.
  • Electronic health record phenotyping and knowledge of Bayesian, high-dimensional, or causal inference methods.
  • Software engineering practices, reproducible pipelines, cloud computing, trusted research environments, or statistical genetics methods development.

Compensation and growth

  • The company states that salaries are externally benchmarked annually.
  • The package includes career progression and access to external courses and learning materials.

Benefits and leave

  • The package includes annual leave, bank holidays, a year-end company shutdown, pension, private health insurance, critical illness cover, life assurance, and enhanced paid family leave.
  • Additional offerings include flexible working, a cycle-to-work scheme, and company social activities.

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