Sr Architect
Full Job Posting
AI-enabled solution architecture
· Lead end-to-end architecture for assigned AI-enabled and automation initiatives, spanning applications, data and knowledge, models, orchestration, agents, APIs, integration, cloud services, identity, security, observability, and operations.
· Translate business outcomes, functional needs, non-functional requirements, and regulatory obligations into architecture options, technical designs, and implementation guidance.
· Design for production scalability, resilience, performance, interoperability, maintainability, portability, and reuse, including workload sizing, capacity assumptions, failure modes, service limits, and operational dependencies.
· Define and develop practical patterns for generative AI, machine learning, intelligent workflows, agentic automation, retrieval and context, tool integration, human oversight, and exception handling when relevant to the project.
AI scalability, economics & operational readiness
· Make cost a first-class architecture concern by assessing consumption drivers such as model usage, tokens, compute, storage, data movement, licensing, vendor services, and support effort.
· Create cost and capacity scenarios for prototype, launch, and scaled adoption; identify material cost-performance-quality trade-offs; and recommend fit-for-purpose models, hosting patterns, caching, routing, batching, quotas, and scaling controls.
· Embed telemetry, usage metering, cost attribution, budgets or thresholds, performance monitoring, quality evaluation, and operational alerts into the solution design so teams can make evidence-based scale, optimize, or stop decisions.
· Partner with platform, FinOps, operations, and product stakeholders to establish ownership, service expectations, support models, lifecycle controls, and continuous optimization practices before production adoption.
· Evaluate build, buy, reuse, and retire options using business value, total cost, architecture fit, delivery risk, security, compliance, vendor dependency, and long-term operability.
Automation advancement across core technology
· Identify and shape high-value automation opportunities across Enterprise Architecture and Enterprise Technology & Platforms, to streamline, simplify and elevate intelligence related to complex technical service delivery processes.
· Advance automation-as-a-capability by designing reusable workflows, APIs, events, templates, policy-as-code, architecture-as-code, and paved-road patterns that reduce manual effort and improve consistency.
· Lead focused proofs of value and production pilots with clear hypotheses, success measures, guardrails, and exit criteria; convert validated learning into reusable patterns, backlog recommendations, standards, or scaled implementation plans.
· Promote human-centered automation that preserves appropriate review, accountability, transparency, and fallback paths for material decisions and regulated processes.
Architecture governance, security & responsible AI
· Apply enterprise architecture principles, approved technology standards, security and privacy requirements, data governance, responsible AI expectations, and regulatory controls throughout the delivery lifecycle.
· Apply project guardrails for data handling, model and provider use, identity and access, content safety, prompt and configuration management, intellectual property, auditability, evaluation, monitoring, human oversight, and incident response.
· Facilitate architecture reviews, document decisions and exceptions, surface material risks and dependencies early, and drive accountable remediation with delivery owners.
· Assess emerging technologies and vendors through structured experiments and architecture reviews, separating credible enterprise value from unsupported novelty.
Delivery leadership, collaboration & knowledge transfer
· Provide architectural leadership at the project level throughout discovery, planning, design, backlog refinement, implementation, testing, release, and transition to operations; remain engaged to validate that delivered solutions conform to approved architecture.
· Collaborate closely with solution architects, engineers, data teams, platform teams, security, operations, product managers, program leaders, and business stakeholders to resolve cross-domain decisions and delivery constraints.
· Communicate complex technology choices in clear business terms, including value, cost, risk, quality, scalability, and delivery implications; present recommendations to architecture and project governance forums.
· Collaborate across teams to develop reusable reference architectures, patterns, templates, decision guidance, and implementation assets; contribute lessons learned to the Enterprise Architecture community of practice.
· Mentor architects and engineers through project work, design reviews, pairing, and knowledge sharing, while retaining the role’s individual-contributor focus.
QUALIFICATION REQUIREMENTS
· Bachelor’s degree in Computer Science, Engineering, Information Systems, Data Science, or a related field; master’s degree preferred. Equivalent experience, skills, and education will be considered.
· Minimum of 5 years of experience in software, solution, enterprise, cloud, platform, data, or AI architecture, with demonstrated delivery of large-scale or business-critical systems.
· Experience designing and guiding complex solutions across cloud, applications, data, APIs, integrations, security, and operational environments.
· Working knowledge of modern AI architecture, including generative AI, model and provider selection, retrieval and context patterns, agents and tool use, MLOps or LLMOps, evaluation, observability, and responsible AI controls.
· Demonstrated ability to design for scalability and reliability and to analyze technology economics, consumption-based services, capacity, total cost, and cost-performance-quality trade-offs.
· Experience advancing automation through APIs, workflow platforms, event-driven integration, infrastructure or policy as code, platform engineering, DevSecOps, or similar methods.
· Strong problem-solving, facilitation, communication, and documentation skills, with the ability to influence across functions and explain technical decisions to both engineering and business audiences.
· Ability to work independently, lead project architecture through ambiguity, manage competing constraints, and drive decisions and outcomes without relying on direct authority.
Preferred qualifications
- · Experience in a regulated industry, healthcare, life sciences, or clinical and commercial technology environments.
- · Experience with enterprise architecture methods, product operating models, Agile delivery, architecture decision records, technology governance, and portfolio or lifecycle management.
- · Relevant architecture, cloud, data, AI, security, automation, Agile, IT service management, or FinOps certifications.
- Get to know Syneos Health
- Over the past 5 years, we have worked with 94% of all Novel FDA Approved Drugs, 95% of EMA Authorized Products and over 200 Studies across 73,000 Sites and 675,000+ Trial patients.
- No matter what your role is, you’ll take the initiative and challenge the status quo with us in a highly competitive and ever-changing environment. Learn more about Syneos Health.
- http://www.syneoshealth.com
- Additional Information
- Tasks, duties, and responsibilities as listed in this job description are not exhaustive. The Company, at its sole discretion and with no prior notice, may assign other tasks, duties, and job responsibilities. Equivalent experience, skills, and/or education will also be considered so qualifications of incumbents may differ from those listed in the Job Description. The Company, at its sole discretion, will determine what constitutes as equivalent to the qualifications described above. Further, nothing contained herein should be construed to create an employment contract. Occasionally, required skills/experiences for jobs are expressed in brief terms. Any language contained herein is intended to fully comply with all obligations imposed by the legislation of each country in which it operates, including the implementation of the EU Equality Directive, in relation to the recruitment and employment of its employees. The Company is committed to compliance with the Americans with Disabilities Act, including the provision of reasonable accommodations, when appropriate, to assist employees or applicants to perform the essential functions of the job.
About Syneos Health
Integrated biopharmaceutical solutions from lab to life.
Visit company websiteJobs and hiring trendsApply for this job in 1 click
Skip the repetitive application forms
Install the Base Career Chrome Extension and autofill job applications across major job boards with your profile.
Trusted by over 500,000 job seekers on Base Career
More from this employer
More jobs at Syneos Health
Sr Global Feasibility Lead - Sponsor dedicated (UK, Poland, Spain or US)
, GBR
Syneos Health is seeking a sponsor-dedicated global feasibility lead to assess clinical trial feasibility, analyze scientific and clinical data, and advise on site identification and recruitment. Applicants need a scienc
Sponsor Dedicated - Sr. Principal Medical Writer - Regulatory Submission Docs (ISE/ISS/Clinical Overview - Must Have)
, USA
Sr. / Principal Medical Writer (Regulatory focus) - Sponsor-dedicated; NA/CAN/UK
, CAN
Sr Global Feasibility Lead - Sponsor dedicated (UK, Poland, Spain or US)
, GBR
Médecin - Ville de Québec
Québec, CAN
Sponsor Dedicated - Sr. Principal Medical Writer - Regulatory Submission Docs (ISE/ISS/Clinical Overview - Must Have)
, USA
eTMF System Manager
Hyderabad, IND
Sr Site Activation Manager
, USA
Clinical Trial Manager I - Site Care Partner
, IND
Clinical Trial Manager RWLP
, USA
Sr. / Principal Medical Writer (Regulatory focus) - Sponsor-dedicated; NA/CAN/UK
, CAN