Scientist, Delivery Screening Technology, Horns Lab

Requirements

• PhD in cell or molecular biology, genetics, biochemistry, bioengineering, or a related field with 0-5 years of relevant post-PhD experience in academia and/or industry.
• Deep hands-on experience in pooled screening with end-to-end ownership, including library design and construction, screen execution, NGS readout, and hit calling and analysis.
• Demonstrated track record of developing and validating novel quantitative molecular assays from scratch, with strong troubleshooting skills.
• Fluency with mammalian cell culture and cell engineering, including construct design, cloning, and characterization of genetically modified cells.
• Proficiency with flow cytometry, including selection for pooled screens.
• Ability to analyze large and complex data sets using Python, R, or similar tools.
• Strong quantitative aptitude and rigorous approach to experimental design.
• Strong project management skills with the ability to plan, execute, and deliver results on time.
• Excellent written and verbal communication skills.
• Demonstrated ability to work in a fast-paced environment and be both an independent thinker and a collaborative team player.
• Preferred Qualifications
• Experience with mammalian synthetic biology, including reporter design or genetic circuit engineering, is a plus.
• Experience with protein engineering, directed evolution, or deep mutational scanning is a plus.
• Experience with relevant cell biology (e.g. endocytosis, receptor trafficking, endosomal escape) or virology (viral entry, fusogens, pseudotyping, egress) is a plus.
• Experience with computational protein design or genome mining is a plus.
• Experience with animal handling and procedures (e.g. injection, tissue collection) is a plus.
• Prior experience in drug delivery, nanomedicine, extracellular vesicles, viral vectors, or lipid nanoparticles is welcome, but not required. We are equally interested in candidates from functional genomics, high-throughput screening, protein engineering, virology, and mammalian synthetic biology who are excited to apply those skills to a new problem domain.
• How to Apply
• Please submit:
• CV
• Brief cover letter describing your research interests, what kinds of projects you’re excited to lead, and why the Horns Lab is a fit. Please be sure to include contact information for 3+ references.
• The base salary range for this position is $121,250 to $159,500. These amounts reflect the range of base salary that the Institute reasonably would expect to pay a new hire or internal candidate for this position. The actual base compensation paid to any individual for this position may vary depending on factors such as experience, market conditions, education/training, skill level, and whether the compensation is internally equitable, and does not include bonuses, commissions, differential pay, other forms of compensation, or benefits. This position is also eligible to receive an annual discretionary bonus, with the amount dependent on individual and institute performance factors.