Principal Engineer - Front/Back-End Development, Azure, CI/CD & AI/Cloud
Role Overview
The Principal Engineer provides senior technical leadership and management for software engineering teams responsible for designing, developing, and delivering scalable, secure, and AI-enabled business solutions.
This role combines engineering management, solution architecture, and hands-on technical expertise to drive the successful delivery of cloud-native applications and modern software platforms.
The Principal Engineer partners with business stakeholders, product owners, architects, and engineering teams to define technical strategy, translate business requirements into scalable solutions, and ensure the successful execution of complex initiatives.
This role is responsible for leading software development teams, guiding architectural decisions, establishing engineering best practices, and fostering a culture of innovation, continuous improvement, and technical excellence.
The ideal candidate brings strong experience in modern software development, cloud-native architectures, AI-enabled solutions, engineering leadership, and delivery execution across Azure, AWS, and other cloud platforms, with preferred experience in Microsoft Azure technologies.
Key Skills for This Role
Full Job Posting
Qualifications
- Bachelor's degree in Computer Science, Engineering, Information Technology, or a related field; equivalent experience will be considered.
- 5+ years of software engineering experience with demonstrated technical leadership responsibilities.
- Experience managing and mentoring software engineering teams and driving delivery outcomes.
- Strong experience designing and delivering cloud-native applications using Microsoft Azure, AWS, or comparable cloud platforms.
- Preferred experience with Microsoft Azure Servless, PaaS services including App Services, Azure Functions, Container Apps, Azure OpenAI, Azure SQL, GitHub Actions, Azure Key Vault, and related cloud-native capabilities.
- Experience developing modern web applications using technologies such as Python, Node.js, TypeScript, C#, React, Next.js, or similar frameworks.
- Strong understanding of software architecture principles, distributed systems, event-driven architectures, APIs, microservices, and cloud-native design patterns.
- Experience with relational and NoSQL databases including PostgreSQL, SQL Server, MySQL, Cosmos DB, DynamoDB, or similar technologies.
- Experience implementing CI/CD pipelines, Infrastructure as Code (Terraform, Bicep, Pulumi, or similar), and DevOps practices.
- Experience integrating applications, platforms, and third-party systems through APIs and cloud services.
- Familiarity with Generative AI, Large Language Models (LLMs), Agentic AI solutions (e.g.: LangChain, OpenAI Agents SDK), AI-assisted development, and modern automation practices.
- Excellent problem-solving, decision-making, communication, and stakeholder management skills.
- Proven ability to lead technical workstreams while remaining an effective hands-on contributor.
Preferred Qualifications
- Experience leading engineering teams in consulting, professional services, or customer-facing environments.
- Experience building AI-enabled or AI-native software solutions.
- Experience with Azure AI Foundry, Azure OpenAI, machine learning platforms, or intelligent automation technologies.
- Experience with modern testing frameworks, automated quality assurance, performance testing, and observability platforms.
- Experience working in regulated or highly governed enterprise environments.
- Azure, AWS, or related cloud certifications.
- Advanced degree in Computer Science, Engineering, or a related technical discipline.
- Get to know Syneos Health
- Over the past 5 years, we have worked with 94% of all Novel FDA Approved Drugs, 95% of EMA Authorized Products and over 200 Studies across 73,000 Sites and 675,000+ Trial patients.
- No matter what your role is, you’ll take the initiative and challenge the status quo with us in a highly competitive and ever-changing environment. Learn more about Syneos Health.
- http://www.syneoshealth.com
- Additional Information
- Tasks, duties, and responsibilities as listed in this job description are not exhaustive. The Company, at its sole discretion and with no prior notice, may assign other tasks, duties, and job responsibilities. Equivalent experience, skills, and/or education will also be considered so qualifications of incumbents may differ from those listed in the Job Description. The Company, at its sole discretion, will determine what constitutes as equivalent to the qualifications described above. Further, nothing contained herein should be construed to create an employment contract. Occasionally, required skills/experiences for jobs are expressed in brief terms. Any language contained herein is intended to fully comply with all obligations imposed by the legislation of each country in which it operates, including the implementation of the EU Equality Directive, in relation to the recruitment and employment of its employees. The Company is committed to compliance with the Americans with Disabilities Act, including the provision of reasonable accommodations, when appropriate, to assist employees or applicants to perform the essential functions of the job.
About Syneos Health
Integrated biopharmaceutical solutions from lab to life.
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