Biomedical Engineer (Clinical, Genomics, Stem cell, GMP Peptide Production)

Overview

Key Responsibilities

• Design, develop, and maintain biomedical instrumentation in a clinical pathology environment (e.g., Roche Cobas Pure and other clinical analyzers).
• Integrate and optimize genomic workflows, including whole genome sequencing (WGS) using MGI, PacBio, & Element Bioscience platforms.
• Operate and maintain liquid handling systems (e.g., Hamilton, Beckman Coulter, Eppendorf, Tecan) to automate clinical, genomic, and peptide assays.
• Lead and support stem cell processes, including cell culturing, differentiation, and organoid development, ensuring precision and reproducibility.
• Conduct GMP peptide synthesis workflows, using mass spectrometry (LC-MS), HPLC, and other analytical techniques.
• Perform in-house calibration of instruments to ensure accuracy and compliance with GMP standards.
• Collaborate closely with automation and robotics engineers to integrate autonomous systems into the facility, ensuring a fully automated, autonomous workflow.
• Collaborate in biobanking processes, ensuring sample integrity, tracking, and storage.
• Support stem cell platform operations and experimental design, ensuring precise protocols.
• Conduct mass spectrometry analysis (LC-MS) for peptide validation and biomarker discovery.
• Troubleshoot technical issues with instruments and provide timely solutions to maintain workflow efficiency.
• Maintain strong communication and collaborate cross-functionally with clinical teams, researchers, IT, and automation/robotics teams, fostering a culture of innovation and teamwork.
• Maintain up-to-date knowledge of emerging technologies in clinical diagnostics, genomics, stem cell research, mass spectrometry, and GMP practices.

Qualifications

• Bachelor’s or Master’s degree in Biomedical Engineering, Clinical Engineering, or related field; PhD is a plus.
• Minimum of 3-5 years of hands-on experience in clinical pathology, working with instruments like Cobas Pure.
• Strong experience with genomic sequencing platforms and liquid handling automation (e.g., Hamilton, Beckman Coulter, Tecan, Eppendorf).
• Experience in GMP peptide synthesis, mass spectrometry (LC-MS), and HPLC for peptide validation and biomarker analysis.
• Familiarity with stem cell platforms, including cell culturing and organoid development.
• Ability to perform in-house calibration of instruments to ensure precise performance and GMP compliance.
• Ability to work closely with automation and robotics engineers to integrate autonomous systems and drive facility-wide automation.
• Proficiency in troubleshooting advanced biomedical equipment and ensuring GMP compliance.
• Strong analytical skills, with attention to detail, and ability to work in a regulated GMP environment.

Education

• Bachelor's (Required)

Experience

• Clinical Pathology: 3 years (Required)
• genomic sequencing platforms and liquid handling automation : 3 years (Preferred)
• GMP peptide synthesis, mass spectrometry : 3 years (Preferred)