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Applications Lab Associate II

Twist Bioscience
San Francisco, USA
Mid · 3–5 years experience
Discovered 1 months ago

Full Job Posting

What You’ll Be Doing

Execute NGS library preparation, target enrichment, and sequencing workflows according to established protocols

Process samples for NGS analysis while meeting production schedules and customer timelines

Perform routine molecular biology techniques including PCR/qPCR, DNA quantification, purification (e.g., SPRI), and electrophoresis

Operate and maintain laboratory equipment, including liquid handling robots and sequencing platforms

Troubleshoot experimental and equipment-related issues to ensure continuity of workflows

Track multiple projects and samples simultaneously, ensuring accurate and detailed documentation (including batch records and deviations)

Analyze experimental data and contribute to interpretation of results

Support development, optimization, and execution of NGS-related protocols and workflows

Maintain digital files and records associated with sequencing runs

Ensure compliance with regulatory standards (e.g., ISO 13485) and internal quality requirements

Support general lab operations including cleaning, restocking, and maintaining a well-organized workspace

Collaborate effectively with cross-functional teams under aggressive timelines

What You’ll Bring to the Team

B.S. or M.S. in Molecular Biology, Biochemistry, Chemistry, or a related field (Associates degree with relevant experience may be considered)

Hands-on experience in molecular biology techniques such as PCR, DNA purification, quantification, and library preparation

Experience working in a laboratory environment with strong attention to detail and documentation practices

Ability to manage multiple tasks and prioritize effectively in a fast-paced environment

Strong organizational, planning, and problem-solving skills

Excellent interpersonal and communication skills with a collaborative mindset

Self-motivated with a commitment to delivering high-quality results

Preferred Qualifications

3–5 years of experience in molecular biology, NGS workflows, or a related field

Direct experience with NGS platforms (e.g., Illumina, PacBio, Element, ONT) and associated sample preparation workflows

Experience with NGS library preparation and target enrichment workflows

Experience with a range of NGS applications DNA, RNA, and Methylation assays

Strong familiarity with analytical tools such as BioAnalyzer or TapeStation, Qubit fluorometry and Nanodrop spectrophotometry

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