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Scientist I, Preformulation

Cytokinetics
South San Francisco, USA
Full-time
Mid
Onsite
Discovered 2 weeks ago
Communication

Full Job Posting

Education and Experience

  • M.S. or Ph.D. in Pharmaceutical Sciences, Chemistry, or a related discipline.
  • M.S. with 7 or more years, or Ph.D. with 4 or more years, of relevant industry experience in preformulation and preclinical formulation development.
  • Hands-on experience formulating poorly water-soluble compounds in a discovery research setting to maximize exposure in animal studies.
  • Hands-on experience with HPLC/UPLC analysis and method development.
  • Hands-on experience with dose verification and with solubility assays in simulated gastric fluid (SGF) and biorelevant media (FaSSIF and FeSSIF), performed in accordance with USP methods.
  • Strong technical knowledge of physicochemical and solid-state properties and their relationship to drug product design and performance.
  • Practical experience selecting and developing solubility-enabling formulations.
  • Practical experience with analytical method development across chromatographic techniques, with working familiarity with mass spectrometry.
  • Ability to manage several projects concurrently, using initiative and creativity to meet agreed objectives and timelines.
  • Excellent written and oral communication skills, including the ability to present technical results to research and CMC audiences.

Required Skills

  • Strong technical knowledge of physicochemical and solid-state properties and their relationship to drug product design and performance.
  • Practical experience selecting and developing solubility-enabling formulations.
  • Practical experience with analytical method development across chromatographic techniques, with working familiarity with mass spectrometry.
  • Ability to manage several projects concurrently, using initiative and creativity to meet agreed objectives and timelines.
  • Excellent written and oral communication skills, including the ability to present technical results to research and CMC audiences.

Preferred Skills

  • Knowledge of biopharmaceutics and pharmacokinetic principles.
  • Experience supporting GLP toxicology studies, including dose formulation analysis.
  • Experience overseeing formulation or analytical work at contract research organizations.
  • Demonstrated problem-solving ability and excellent practical laboratory skills.
  • Strong collaboration and networking skills, with the ability to engage colleagues in new initiatives.
  • Ability to deliver reliably under competing priorities and timelines.
  • #LI-ONSITE
  • Pay Range:
  • The expected salary range for this position based on the primary location of South San Francisco, CA is $135,000-$157,500. The base pay offered will take into account internal equity and may vary depending on the candidate's geographic region, job-related knowledge, skills, and experience among other factors. Base salary is just one component of our competitive total compensation package, which includes equity in the form of stock options and/or restricted stock units, comprehensive health, dental, vision, life and disability insurance coverage, 401k retirement benefits with employer match, learning and wellness stipends, and paid time off. Note that benefits are subject to change and may vary based on jurisdiction of employment.
  • Our employees come from different backgrounds, and we celebrate those differences. We are looking for the best candidates for our open roles, but do not expect applicants to meet every qualification in order to be considered. If you are excited about what you could accomplish at Cytokinetics and believe you can add value to our team, we would love to hear from you.
  • Please review our General Data Protection Regulation (GDPR) policy PRIOR to applying.
  • Our passion is anchored in robust scientific thinking, grounded in integrity and critical thinking. We keep the patient front and center in all we do – all actions and decisions are in service of the patient and their caregivers. We champion integrity, ethics, doing the right thing, and being our best selves.
  • Fraud Warning: How to Identify Impersonated Cytokinetics Job Postings and Offers
  • Recently, there have been fraudulent employment offers being sent to candidates on behalf of Cytokinetics. Please be advised that all legitimate offers from Cytokinetics will come directly from our official email domain (Cytokinetics.com) and will only be made after completing a formal interview process.
  • Here are some ways to check for authenticity:
  • We do not conduct job interviews through non-standard text messaging applications
  • We will never request personal information such as banking details until after an official offer has been accepted and verified
  • We will never request that you purchase equipment or other items when interviewing or hiring
  • If you are unsure about the authenticity of an offer, or if you receive any suspicious communication, please contact us directly at [email protected]
  • Please visit our website at: www.cytokinetics.com
  • Cytokinetics is an Equal Opportunity Employer

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