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Principal Scientist, Data Science – AI & Generative AI Systems – R&D DDSAI – Therapeutics Development & Supply (TDS)

Johnson & Johnson
Spring House, USA
Full-time
Senior · 3+ years experience
Hybrid
Discovered 1 weeks ago
python

Full Job Posting

KEY RESPONSIBILITIES

  • AI Solution Development & Delivery
  • Design, build, test, and deploy AI solutions for documentation, knowledge retrieval, evidence synthesis, and decision support in the TDS ecosystem.
  • Build agentic AI workflows that coordinate models, tools, data, and human review across multi-step scientific and supply chain processes.
  • Develop reusable AI capabilities aligned with DDSAI AI/ML architecture and platform standards.
  • Translate scientific, regulatory, and operational needs into scalable AI systems for regulated environments.
  • Technical Rigor & Responsible AI
  • Establish evaluation frameworks for LLM systems, including rubrics, traceability, robustness, uncertainty, and usability.
  • Apply responsible AI practices, including human-in-the-loop validation, risk assessment, content safety, and governance.
  • Maintain strong software engineering practices, including modular design, testing, documentation, and lifecycle management.
  • Contribute to best practices for LLM, RAG, and agentic AI systems across DDSAI and TDS.
  • Cross-Functional Collaboration
  • Partner with regulatory, quality, CMC, scientific, and technical stakeholders to define use cases, validate outputs, and drive adoption.
  • Collaborate with DDSAI AI/ML on infrastructure, architecture, evaluation, and reusable components.
  • Communicate system behavior, risks, and tradeoffs to both technical and non-technical stakeholders.

QUALIFICATIONS

  • Required
  • Degree in Engineering, Data Science, Life Sciences, Computer Science, or related field; advanced degree preferred.
  • 3–5+ years of hands-on experience building and deploying AI, NLP, or generative AI solutions, including large language models (LLMs).
  • Experience in Pharmaceutical Product Development, including Chemistry, Manufacturing and Controls (CMC)
  • Strong proficiency in Python
  • Strong communication skills, with the ability to explain technical topics to non-technical stakeholders.
  • Preferred
  • Experience with open-source agentic frameworks (e.g., LangGraph, DSPy, mem0, etc.)
  • Experience with retrieval-augmented generation, embeddings, vector databases, and model evaluation.
  • Exposure to working in regulated environments (GxP)
  • Familiarity with responsible AI frameworks, content safety practices, and AI governance in regulated environments.
  • Why This Role Is Unique
  • This is a rare opportunity to grow in one of the world’s most ambitious and fast-growing R&D Data Science organizations, shaping how Therapeutics Development & Supply data powers next‐generation therapies in the largest biomedical company on the planet. Your work will directly accelerate Johnson & Johnson’s scientific discovery, fuel AI innovation, and impact patients globally.
  • Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.
  • Johnson & Johnson is committed to providing an interview process that is inclusive of our applicants’ needs. If you are an individual with a disability and would like to request an accommodation, external applicants please contact us via https://www.jnj.com/contact-us/careers, internal employees contact AskGS to be directed to your accommodation resource.
  • #JRDDS
  • #JNJDataScience
  • JNJIMRND-DS

Preferred Skills:

  • Advanced Analytics, Coaching, Critical Thinking, Data Analysis, Data Privacy Standards, Data Quality, Data Reporting, Data Savvy, Data Science, Data Visualization, Digital Fluency, Econometric Models, Organizing, Process Improvements, Strategic Thinking, Technical Credibility, Workflow Analysis
  • The anticipated base pay range for this position is:
  • $117,000.00 - $201,250.00
  • Additional Description for Pay Transparency:
  • Subject to the terms of their respective plans, employees are eligible to participate in the Company’s consolidated retirement plan (pension) and savings plan (401(k)). This position is eligible to participate in the Company’s long-term incentive program. Subject to the terms of their respective policies and date of hire, employees are eligible for the following time off benefits: Vacation –120 hours per calendar year Sick time - 40 hours per calendar year; for employees who reside in the State of Colorado –48 hours per calendar year; for employees who reside in the State of Washington –56 hours per calendar year Holiday pay, including Floating Holidays –13 days per calendar year Work, Personal and Family Time - up to 40 hours per calendar year Parental Leave – 480 hours within one year of the birth/adoption/foster care of a child Bereavement Leave – 240 hours for an immediate family member: 40 hours for an extended family member per calendar year Caregiver Leave – 80 hours in a 52-week rolling period10 days Volunteer Leave – 32 hours per calendar year Military Spouse Time-Off – 80 hours per calendar year For additional general information on Company benefits, please go to: - https://www.careers.jnj.com/employee-benefits
  • Degree in Engineering, Data Science, Life Sciences, Computer Science, or related field; advanced degree preferred.
  • Preferred
  • Subject to the terms of their respective plans, employees are eligible to participate in the Company’s consolidated retirement plan (pension) and savings plan (401(k)).
  • This position is eligible to participate in the Company’s long-term incentive program.
  • Vacation –120 hours per calendar year
  • Sick time - 40 hours per calendar year; for employees who reside in the State of Colorado –48 hours per calendar year; for employees who reside in the State of Washington –56 hours per calendar year
  • Holiday pay, including Floating Holidays –13 days per calendar year
  • Work, Personal and Family Time - up to 40 hours per calendar year
  • Parental Leave – 480 hours within one year of the birth/adoption/foster care of a child
  • Bereavement Leave – 240 hours for an immediate family member: 40 hours for an extended family member per calendar year
  • Caregiver Leave – 80 hours in a 52-week rolling period10 days
  • Volunteer Leave – 32 hours per calendar year
  • Military Spouse Time-Off – 80 hours per calendar year
  • For additional general information on Company benefits, please go to: - https://www.careers.jnj.com/employee-benefits

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