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Postdoctoral Scientist - Drug Delivery Experimental Fluid Dynamics

Eli Lilly and Company
USA
Full-time
Mid · 3+ years experience
Onsite
Discovered 3 weeks ago

Full Job Posting

Key Responsibilities:

  • Design and execute in vitro aerosol characterization experiments using experimental fluid dynamics techniques — physical measurements, flow visualization, and benchtop models — on pulmonary and nasal device platforms, assessing droplet size distribution (laser diffraction, cascade impaction), delivered dose, and delivery efficiency.
  • Apply working knowledge of pulmonary and nasal tissue physiology (airway and mucosal anatomy, mucus rheology, and regional structures relevant to deposition and clearance) to design physiologically representative benchtop and ex vivo experimental models, accounting for anatomical variability and its effects on precision and targeting.
  • Apply and interpret existing computational fluid dynamics (CFD) or physiologically based pharmacokinetic/deposition (PBPK/PBPD) models — including uncertainty quantification and sensitivity analysis — to complement experimental data and predict regional aerosol deposition and IVIVC linkages (MMAD, FPF, delivered dose to in vivo or PK/PD endpoints) across patient-representative airway geometries.
  • Collaborate with formulation scientists, device engineers, and translational scientists to integrate experimental and physiological findings into formulation optimization, design space definition, and actionable insights.
  • Communicate findings through internal technical reports, cross-functional presentations, and peer-reviewed publications, and participate in structured mentorship and professional development programming within Lilly’s postdoctoral research community.

Basic Qualifications:

  • Earned Ph.D. in Biomedical Engineering, Physiology, Mechanical Engineering, Chemical Engineering, Aerosol Science, or a closely related field, conferred within the past 3 years.
  • Demonstrated hands-on experience in experimental fluid dynamics — physical measurements, flow visualization, and benchtop or physiologically representative models of fluid and particle transport
  • Experience designing and executing hands-on experiments and applying characterization techniques (e.g., next-generation impactor [NGI], laser diffraction, DUSA)
  • Working knowledge of tissue physiology and anatomy (ideally airway/mucosal structure, mucus properties, and regional anatomy relevant to aerosol deposition and clearance) and ability to apply literature research toward experiment design
  • Strong publication record commensurate with career stage
  • Ability to work both independently and collaboratively in a fast-paced, matrix-based environment.
  • Qualified applicants must be authorized to work in the United States on a full-time basis. Lilly will not provide support for or sponsor work authorization or visas for this role, including but not limited to F-1 CPT, F-1 OPT, F-1 STEM OPT, J-1, H-1B, TN, O-1, E-3, H-1B1, or L-1.
  • Additional Preferences:
  • Familiarity with computational modeling of aerosol transport and/or deposition (e.g., CFD using ANSYS Fluent/OpenFOAM, or lung deposition models such as MPPD) sufficient to evaluate and apply existing modeling frameworks alongside experimental work.
  • Experience with realistic or idealized airway geometry models (e.g., Weibel, stochastic, or CT-derived anatomical models).
  • Prior industry internship or academic–industry collaborative research experience.
  • Self-directed and highly motivated individual who wants to learn new techniques while continually pursuing research and publication goals.
  • Excellent communicator (oral and written) with presentation experience and a strong publication record; proficient in data analysis and reporting.
  • Additional Information:
  • This is a fixed-term role for one year, extendable up to four years, with eligibility to apply for full-time positions upon completion.
  • Position Location: Boston, MA
  • Travel Percentage (%): 10
  • Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form ( https://careers.lilly.com/us/en/workplace-accommodation ) for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.
  • Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status.
  • Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia (AMECA), Black Employees at Lilly (BE@Lilly), Chinese Culture Network (CCN), EnAble, Evolve, Lilly Indian Network (LIN), Organization of Latinx at Lilly (OLA), Pride (LGBTQ+ Allies), Veterans Leadership Network (VLN) and Women’s Initiative for Leading at Lilly (WILL).
  • Actual compensation will depend on a candidate’s education, experience, skills, and geographic location. The anticipated wage for this position is
  • Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly’s compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.
  • #WeAreLilly

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