Peptide Chemist (Night Shift)

About the Role

Responsibilities

• Execute end-to-end peptide synthesis workflows, including resin loading, coupling and deprotection cycles, cleavage, purification, analytical characterization, and sample preparation.
• Run microwave-assisted solid-phase peptide synthesis and support routine synthesizer maintenance.
• Troubleshoot failed couplings, low crude purity, side products, cleavage issues, and instrument downtime.
• Purify and characterize candidates using analytical HPLC, prep HPLC, LC-MS, and related methods.
• Record identity, purity, yield, analytical traces, and batch-level quality-control data before handoff.
• Prepare compounds for in vitro and in vivo testing and maintain accurate experimental records.
• Share synthesis feasibility, purity, yield, stability, and analytical observations that inform what the team designs and makes next.
• This role includes additional pay for working night shifts.
• In addition to the posted salary range, we offer generous equity options.
• Compensation will depend on the skills, experience, and scope of impact you bring. If your background, experience, or compensation needs fall outside this range, we are still open to a conversation based on the scope and impact you could bring.
• $500+ monthly wellness budget for training, supplements, coaching, recovery, or other tools that help you perform at your best.
• Healthcare: We offer a broad range of medical, dental, and vision coverage options, with Capable covering 100% of the base policy.
• You will also have access to HSA, FSA, and 401K plans.
• Healthy dinners with the team are provided daily.
• We support visa sponsorship where appropriate, including O-1, H-1B, J-1, TN, and other employment-based pathways. Our team is already international, with members from Canada, Pakistan, Germany, Austria, Switzerland, China, India, and the United States.
• Our process is fast, transparent, and personal. We care about getting to know the person behind the application.
• Initial application
• First phone screen
• Second phone screen
• In-person work trial in San Francisco: designed to give both sides a realistic sense of working together. Get to know the founding team!
• Curious but not sure? Apply anyway. It takes 5 minutes, and you do not need to be actively job searching to start a conversation.
• Some of the best people do not map perfectly to a job description. If this sounds like a place where you could do important work, we would like to hear from you.
• And if someone exceptional comes to mind, send them our way here. We read every referral carefully, and if your referral joins Capable, we’ll send you a thank-you bonus.

Pay & Benefits

Application Process

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Equal Opportunity