Manager, IT Operations

eGenesis is a clinical-stage biotechnology company developing human-compatible engineered organs to address the severe global organ shortage. The Company’s proprietary genome engineering platform enables extensive, multiplex gene edits to remove key biological barriers, add protective human transgenes, and inactivate endogenous retroviruses. EGEN-2784, a genetically engineered porcine kidney, is the Company’s lead program and is currently being evaluated in a multi-patient Expanded Access study at MGH. eGenesis is headquartered in Cambridge, MA. At eGenesis, our core values—innovation, collaboration, compassion, resilience, and passion—are at the center of how we work. We engineer hope and bring passion to everything we do. We collaborate and learn from one another, combining diverse expertise to tackle complex challenges. We innovate boldly, pushing boundaries and science to new heights. where no pig organ has gone before. With resilience, we navigate challenges and celebrate progress together. And in all we do, we lead with compassion—for our patients, our people, and our pigs.

Lead day-to-day IT operations and service delivery across all four eGenesis sites

Manage the service desk in Freshservice, including queue management, prioritization, escalation handling, and quality of support

Direct the work of managed service providers and support vendors, monitor vendor SLAs, and manage escalations through resolution

Administer Microsoft 365, Entra ID, and Intune, including device compliance and security policies, conditional access, application deployment, and license management

Manage the employee technology lifecycle, including onboarding, role changes, offboarding, and hardware provisioning and recovery

Support endpoints (Windows and macOS), mobile devices, printers, conference rooms, and site infrastructure

Support laboratory instrument workstations, connected lab systems, and lab software, coordinating with lab operations teams and instrument vendors

Coordinate incident response for outages and service disruptions across internal staff and vendors, and drive issues to root cause

Follow and enforce change control practices for changes affecting GxP systems, including documentation and closure evidence

Perform periodic access reviews and support security operations, audits, and compliance activities

Manage vendor contracts, quotes, purchase orders, renewals, and invoice review for IT services, hardware, and software

Maintain accurate asset inventory, software and license records, documentation, and runbooks

Lead operational projects such as office buildouts, hardware refreshes, and system rollouts from planning through verification

Support the rollout, administration, and user enablement of approved AI tools in partnership with IT leadership

Track and report service metrics, risks, and recurring problems to IT leadership with recommendations

Serve as a liaison between IT and other business units for operational needs