pinpoint
Machine Learning Scientist
BigHat Biosciences
San Mateo, USA
Full-time
Senior
Hybrid
USD 150000-200000 yearly / year
Discovered 1 months ago
PythonPyTorchCI/CDAWSLLMs
Key Skills for This Role
PythonPyTorchCI/CDAWSLLMs
Full Job Posting
Key Responsibilities
- Design and implement the next state-of-the-art generative models of antibody sequence and structure, and predictive models of antibody properties, trained on proprietary internal datasets of thousands to millions of antibodies.
- Develop multi-modality, multi-objective iterative protein sequence optimization approaches to lab-in-the-loop antibody design problems for validation and deployment in our high-throughput wet lab - at BigHat success is only declared upon synthesis of real antibodies with drug-like properties.
- Develop, refine, and deploy agentic and LLM-driven optimization methods to further automate and accelerate our design-build-test loop.
- Provide ML expertise and support for ongoing therapeutics programs, directly contributing to the development of new drugs.
- Collaborate with our engineering team to ensure maximal efficiency in the automated deployment of our latest models and methods.
- Work closely with an interdisciplinary team of drug developers, wet lab scientists, automation specialists, data scientists, etc. - every therapeutics program at BigHat is heavily interdisciplinary.
Skills Knowledge and Expertise
- PhD in ML/CS/EE or relevant scientific discipline, hands on experience developing and applying novel ML methods and a strong quantitative background.
- Strong competency in Python, familiarity with PyTorch (even without LLMs!) and experience with modern software engineering best practices, including not just agentic/LLM-assisted coding but testing, CI/CD, etc.
- Excellent communication skills, sufficient biomedical domain knowledge to interact effectively with diverse scientific teams.
- Energy and ambition - ready to dive into a fast-paced environment and execute across multiple projects.
- Familiarity with the current state-of-the-art in ML-driven protein engineering
- Nice-to-haves include experience with de novo design, NGS data, Bayesian optimization, familiarity with antibody biology and drug development, experience training and deploying models on AWS, and publications at major ML conferences.
About BigHat Biosciences
Biotechnology98 employeesFounded 2019
Private biotechnology company designing safer, more effective antibody therapies with machine learning and synthetic biology for patients.
Visit company websiteJobs and hiring trendsApply for this job in 1 click
Skip the repetitive application forms
Install the Base Career Chrome Extension and autofill job applications across major job boards with your profile.
Trusted by over 500,000 job seekers on Base Career
More from this employer
More jobs at BigHat Biosciences
Lab Operations Assistant (Part-Time)
San Mateo, USA
Discovered 3 weeks agoPart Time, Contract
Senior Director, Controller
San Mateo, USA
Discovered 1 months agoFull-time
Senior Research Associate, Discovery Medicine
San Mateo, USA
Discovered 1 months agoFull-time
Associate Scientist, Display Technologies
San Mateo, USA
Discovered 1 months agoFull-time
Scientist II, Developability
San Mateo, USA
Discovered 1 months agoFull-time
Principal, Machine Learning Scientist
, USA
Discovered 1 months agoFull-time
Director, Antibody Discovery
San Mateo, USA
Discovered 1 months agoFull-time
Senior Scientist I, Antibody Engineering
San Mateo, USA
Discovered 1 months agoFull-time